- BERBERIS ROOT EXTRACT STANDARDISED TO 2% BERBERINE
- BERBERINE PROMOTES LIVER HEALTH
- CONVENIENT TABLET FORM
- BERBERINE INFLUENCES GLUCOSE METABOLISM
- AS MANY AS 90 PORTIONS PER PACK
SFD ADAPTO BERBERINE is a dietary supplement containing berberis root extract (Berberis aristata) in tablets, standardised to 2% berberine. The product contains up to 90 servings for consumption. This alkaloid, which is present in various plant parts such as bark, roots or leaves, is often used for its properties.
WHAT IS BERBERINE?
Berberine is a natural alkaloid. It is characterised by a unique spectrum of properties and occurs naturally in various plants, especially those of the genus Berberis.
Due to its numerous properties, barberine has already been used in traditional medicine.
THE BENEFICIAL EFFECTS OF BERBERINE
LIVER HEALTH
Research shows that berberine has liver-protective properties. This is due, among other things, to its antioxidant action and its effect on the activity of enzymes responsible for detoxifying the body [1,2].
EFFECTS ON GLUCOSE METABOLISM
A growing number of studies suggest that berberine may be a natural way to improve insulin sensitivity. This may be due to its effect on the expression of so-called lipogenic genes [3]. In addition, berberine, according to many authors, may act similarly to metformin - by directly affecting the activity of AMPK [4, 5], an enzyme whose activation results in inhibition of glucose and fat synthesis. In addition, chronic activation of AMPK resembles the effect of intense exercise [6].
Source:
[1] Zhu X., Guo X., Mao G., Gao Z., Wang H., He Q., Li D.: Hepatoprotection of berberine against hydrogen peroxide-induced apoptosis by upregulation of Sirtuin 1. Phytother Res. 2013 Mar;27(3):417-21
[2] Imenshahidi M., Hosseinzadeh H.: Berberis Vulgaris and Berberine: An Update Review. Phytother Res. 2016 Nov;30(11):1745-1764.
[3] Yun S. Lee, Woo S. Kim, Kang H. Kim, Myung J. Yoon, Hye J. Cho,Yun Shen, Ji-Ming Ye, Chul H. Lee, Won K. Oh, Chul T. Kim, Cordula Hohnen-Behrens, Alison Gosby, Edward W. Kraegen, David E. James, Jae B. Kim: Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States. Diabetes, vol. 55, August, 2006, 2256 – 2264.
[4] Nabrdalik K., Cichocka E., Gumprecht J.: Metformina a kinaza białkowa aktywowana przez AMP (AMPK) i procesy energetyczne w cukrzycy typu 2. Diabetologia Kliniczna 2013, tom 2, nr 4. ISSN 2084–4441.
[5] You-Jin Ch., Kang-Yo L., Seung-Hwan J., Hyung Sik K., Gayong S., Mi-Gyeong K., Yu-Kyoung O., Seon-Hee O., Dae Won J., Byung-Hoon L.: Activation of AMPK by berberine induces hepatic lipid accumulation by upregulation of fatty acid translocase CD36 in mice. Toxicology and Applied Pharmacology. Vol. 316, 1 February 2017, p. 74-82.
[6] Nabrdalik K., Cichocka E., Gumprecht J.: Metformina a kinaza białkowa aktywowana przez AMP (AMPK) i procesy energetyczne w cukrzycy typu 2. Diabetologia Kliniczna 2013, tom 2, nr 4. ISSN 2084–4441.
*Due to the limitations of the regulations governing dietary supplements, we regret to inform you that we are unable to provide full details of the properties of some ingredients. We encourage you to visit the official websites to find out more about how the ingredients, formulas, vitamins and minerals work.